Project

Heart Disease, CNS Dysfunction, and Cognitive Outcome in the Elderly

Heart Disease, CNS Dysfunction, and Cognitive Outcome in the Elderly

Principal Investigator: Paul, Robert
September 1, 2000 - August 31, 2005
Funder: National Institute of Aging
Official Title: Heart Disease, CNS Dysfunction, and Cognitive Outcome in the Elderly

Cardiovascular disease (CVD) is a particular concern for the elderly. Cardiac rehabilitation (CR) is recognized as essential in CVD management, though its effectiveness is often limited. This is partially due to an inability of many patients to learn, apply, and modify behavior towards a healthier lifestyle. Neurocognitive impairments are common among elderly CVD patients, reducing their ability to benefit from CR, modify their behavior, and experience improved quality of life. Functional deficits seem to reflect brain dysfunction of cerebrovascular origin, with common vascular etiology. This study will examine the longer-term effect of CVD on the brain, its functions, and its impact on the health status of the elderly. Long-term objectives are to: 1) show that brain in dysfunction is associated with CVD- severity, 2) caused by specific age-related vascular problems, and 3) that associated functional impairments affect both immediate CR- benefit, and longer-term clinical and functional outcome.

Related Projects

Traumatic Stress: New Mechanisms and Effective Treatment

The impacts of a physical trauma are well understood in the medical community, and treatment approaches have become quite advanced. Our ability to study the brain and its reactions to physical and chemical stimuli is relatively new, but growing at incredible speeds. "Traumatic Stress: New Mechanisms and Effective Treatment" will bring together a group of internationally recognized researchers to deliver a whole new perspective on what physically happens in the brain during and following traumatic stress. They will explore not only the physical, but the behavioral and emotional reactions to traumatic stress through the lens of groundbreaking new research. Most importantly, they will offer a fresh perspective on care and treatment. This conference will change how you look at traumatic stress in the brain and what to do about it.

Learn More

Missouri Opioid/Heroin Overdose Prevention & Education (MO-HOPE)

MIMH, partnered with National Council on Alcoholism & Drug Abuse (NCADA), under the leadership of the Missouri Department of Mental Health, is implementing and evaluating a SAMHSA-funded 5-year, $5 million grant to reduce opioid overdose events in the Eastern Region of the state.

Learn More

Missouri Opioid STR

Missouri Opioid STR (State Targeted Response) -
A Comprehensive Approach to Missouri's Opioid Crisis

Learn More