Project

Frailty and Neurocognition in Older HIV Patients

Frailty and Neurocognition in Older HIV Patients

Principal Investigator: Paul, Robert
Funder: National Institute of Nursing
Official Title: Frailty and Neurocognition in Older HIV Patients

Frailty and Neurocognition in Older HIV Patients

The purpose of this research is to study: 1)the effect of HIV on cognitive ability/brain functioning, 2) if older HIV-infected individuals with a combination of cognitive impairment and frailty are more vulnerable than those with one or the other, and 3) if frailty correlates with neuroimaging biomarkers of brain integrity in older HIV-infected individuals. Older (50 yrs. and higher) adults that are HIV+ will go through a series of tests including: neuropsychological (memory) tests, questionnaires to determine mood, ability to care for oneself and drug and alcohol history, an MRI, and a neuromedical examination to examine the nerves in the face, reactions to touch, and reflexes. This information will provide data to increase knowledge of the relationship between physical frailty and neurocognitive impairment in older HIV+ adults, which may lead to future adjunctive therapies.

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