Project

Cognition, Fatigue and Mood in Myasthenia Gravis

Cognition, Fatigue and Mood in Myasthenia Gravis

Principal Investigator: Paul, Robert
June 1, 1999 - May 31, 2001
Funder: National Institute of Neurological Disorders and Stroke
Official Title: Cognition, Fatigue and Mood in Myasthenia Gravis

Individuals with myasthenia gravis (MG) reported experiencing cognitive difficulties, yet the etiology, severity and extent that these problems impact patients’ lives is unknown. MG patients complain of fatigue, but it is not clear if fatigue plays an important role in patients’ experience of cognitive difficulties or if psychiatric illness is related to cognitive difficulties. The specific aims are to determine if MG patients experience cognitive deficits compared to healthy control subjects, and to what extent cognitive difficulties in individuals with the disease may be due to disease activity, cognitive and physical fatigue, or psychiatric illness. This study will examine the relationships between cognition, fatigue and mood disturbance and quality of life in individuals with MG. Data collected will provide critical information relevant to a better understanding of MG symptomatology. Once cognition, fatigue, and psychiatric illness in MG are better understood, appropriate efforts can be directed at providing clinically meaningful intervention.

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